It was only a matter of time before Iggy Azalea responded to Eminem's controversial lyric.

On Wednesday night, Marshall previewed a snippet of a track called "Vegas" with Royce Da 5' 9'' from his upcoming ShadyXV compilation album, which mentioned both Nicki Minaj and Iggy, but his remarks toward The New Classic rapper were a bit shocking -- even coming from him.

On the song, he alludes to rape, while referencing Iggy.

"You’re lucky just to follow my ride/ If I let you run alongside the Humvee, unless you’re Nicki/ Grab you by the wrist, let’s ski/ So, what’s it gon’ be?/ Put that sh-t away, Iggy/ You gon’ blow that rape whistle on me."

On Thursday (November 20), Iggy, who previously revealed that her younger brother is a huge fan of Eminem, took to Twitter to comment on the lyrics.

In her tweets Iggy is clearly referencing her recent social media feud with Snoop Dogg as well. Guess she can't catch a break right now.

She didn't seem too upset by this, though, eventually brushing it off and heading out to AMAs rehearsal. "Women in music have the bigger balls anyhow we endure much more harassment and critic," she wrote. "good morninnggggg!!!!!! off to camera block for AMAs!"

Hear Iggy talk about her little brother's love for Eminem in the video below.