It's MTV's second annual Musical March Madness! MTV News took the 64 biggest names in rock, split them up into four regions, assigned them seeds and puts them up against one another in a single-elimination series of match-ups in a winner-take-all contest. We're leaving it to you to decide an actual champ in this field of 64, so over the next few weeks, fan voting will determine who will emerge as this year's champion. It's all about the fans, and the artist with the most passionate fan base will score the awesome Musical March Madness trophy!

The Sweet 16 spotlight is now pointed directly at the South region, which features another quartet of bands who could easily find themselves holding the 2011 MTV Musical March Madness trophy aloft when all is said and done.

Voting for all Sweet 16 match-ups will close on Tuesday, March 29 at midnight. As always, you can follow all the voting here.

(1) Linkin Park vs. (5) Paramore

Linkin Park have cruised through the first two rounds of the tournament, besting Sleigh Bells and R.E.M. on the way to the Sweet 16. They'll take on their strongest challenger yet in Paramore, who have come through two intense battles against No Doubt and Kings of Leon to emerge as a power in the South region. Which one of these platinum-sellers will continue their push to the finals? Vote to find out!

Check out Dick Bagwell and Vincent Twice previewing the Sweet 16!

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Check out the Musical March Madness bracket and be take a look at the hoops-centric photos of some of the tournament's biggest bands.