It's MTV's second annual Musical March Madness! MTV News took the 64 biggest names in rock, split them up into four regions, assigned them seeds and puts them up against one another in a single-elimination series of match-ups in a winner-take-all contest. We're leaving it to you to decide an actual champ in this field of 64, so over the next few weeks, fan voting will determine who will emerge as this year's champion. It's all about the fans, and the artist with the most passionate fan base will score the awesome Musical March Madness trophy!

The East region marches on with a pair of excellent indie rock favorites taking one another on for Sweet 16 berth. It promises to be a barnburner that should go down to the last day.

Voting for all second round match-ups will close on Sunday, March 27 at midnight. As always, you can follow all the voting here.

(4) The Strokes vs. (5) Phoenix

In the first round, the Strokes took out fellow New York indie darlings MGMT in a reasonably close race, while Phoenix delivered a surprisingly thorough beatdown of Phish (the Phish fans did not come together the way some prognosticators expected). Will the French genre-hoppers be able to upend the New York comeback kings (who may be getting a boost from their well-received new album Angles)? Only your votes know for sure.

Watch the breakdown of the first round and a preview of round two!

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Check out the Musical March Madness bracket and be take a look at the hoops-centric photos of some of the tournament's biggest bands.