How could one little kiss (that went viral) be dripping with so much regret?

Madonna made a cameo during Drake's first headlining set at Coachella 2015, and planted a big, wet one on his lips. For days afterwards, there were jokes about the pained look on Drizzy's face afterwards -- did he actually hate the kiss? -- and now Madonna seems to be saying that she regrets it.

Madge did a Q&A with fans this weekend for "Live with Romeo’s: Saturday Night Online," during which time she fielded two questions about the infamous kiss.

First up: "What advice would you give to your younger self knowing knowing what you know now?"

Keep in mind that Madonna has done a lot of wild things over the years, probably a few that she actually regrets, but her response was, "Don't kiss Drake, no matter how many times he begs you to." Yikes.

And then there was just a little bit more shade, when another fan asked, "Is Drake a good kisser?" The answer to this one wasn't as blunt, but certainly a bit more backhanded. "You asked the million dollar question," she responded, adding, "I kissed a girl and I liked it."

So, no?

Guess she should've just stopped after Britney and Christina.

Watch Madonna's full Q&A below.