From weddings to DNA tests, it often seems like nothing's off-limits when it comes to what the Kardashian clan will share onscreen. But now they're preparing to reveal even more, this time in an interview with Oprah Winfrey.

The most successful reality TV family is set to participate in a rare sit-down with the talk-show queen, and no topic will be off the table. Kim, Kourtney, Khloé, and Rob Kardashian, along with Kendall, Kylie, Kris and Bruce Jenner will meet Winfrey for the first time. Kourtney and Khloé's significant others, Scott Disick and Lamar Odom, respectively, will also be on hand for the chat airing Sunday, June 17, on the flagship OWN show "Oprah's Next Chapter."

The Kardashians' lawyer father, Robert Kardashian, had already made the family name well-known in Hollywood before his death in 2003, serving as the defense attorney in the famed O.J. Simpson trial. But it was Kim who turned the notoriety from a leaked sex tape into real fame when she allowed E! cameras to show the inner workings of her close-knit family.

"Keeping up with the Kardashians" premiered on E! in 2007, making overnight stars and brand icons of the attractive bunch, especially Kim. Six seasons later, the Kardashians signed a three-year deal with the network reportedly worth $40 million.

Winfrey will have the task of addressing a wide range of topics surrounding the Kardashian family. Their most recognizable face, Kim, has been front and center in the news for her very-public relationships with star athletes, including the dissolution of her [article id="1673430"]marriage to the NBA's Kris Humphries[/article] after just 72 days, and her most recent, [article id="1686983"]with Kanye West[/article].

"Oprah's Next Chapter" has become known for intimate celebrity interviews, most [article id="1687054"]recently featuring 50 Cent[/article]

Since Winfrey rarely holds back, it will be interesting to see her interaction with the very media-savvy Kardashian family.

What do you want Oprah to ask the Kardashians? Share your thoughts in the comments!