[artist id="1340778"]Game[/artist] might never pick a lyrical fight with [article id="1668443"]Eminem[/article], but he has no problem sending barbs toward rap great [artist id="1269"]Jay-Z[/artist]. On Wednesday's "RapFix Live," Game clarified that his recently released dis track "Uncle Otis" is not to be taken personally by any of the rappers he took shots at. That list includes: [artist id="860639"]50 Cent[/artist], [artist id="3953557"]Kreayshawn[/artist], [artist id="2811091"]Big Sean[/artist] and, of course, Jay-Z.

" 'Jay' rhymes with a lot of words," Game told MTV News' Sway Calloway. "So whenever you're writing, it always pops in somehow or another. I shoot shots in the dark sometimes, but they ain't to be taken personal."

Game's shots in the dark have ruffled some feathers. His Big Sean swipe caused a stir among the G.O.O.D. Music rapper's fans who took issue with Game on Twitter this past weekend. Sean addressed "Uncle Otis" on July 27 during a radio appearance on Power 105.1's the Breakfast Club morning show in New York City. "I didn't even take it as a dis. I took it as him doing what he do. Don't he got an album that's about to come out?" Big Sean said of Game's verse.

The L.A. rapper takes a swipe at Jay early in the track, making fun of Jigga's age. The Roc Nation rapper is 41 years old. "Here's a dome shot to this n---a named Otis/ N---as think they the coldest, but n---a you just the oldest/ N---as just be chasin' their youth, but it's gone/ Yo 'Ye this n---a ain't even wanna put you on."

Game said he doesn't expect Hov to fire back. "Certain people you know that ain't gonna respond: I don't think Hov is gonna respond, and if he does, it'll be another shot in the dark subliminally or indirect, and I think that's cool because Hov is a legend," he said.

This isn't the first time Game launched insults at Jay. On his 2006 single "It's Okay (One Blood)," the Compton MC rapped, "You 38, and you're still rappin' ugh," a line that Jay actually acknowledged on his 2006 song "The Prelude."

Game appreciates the back and forth. "Anytime that he takes time out of his day to say something like, 'I used to think that rappin' at 38 was ill, till last year I grossed $38 mil,' ... I think it's cool."

Sound off on "Uncle Otis" in the comments below!