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Duets can cross musical lines (Eminem and Elton), create new genres (Run DMC and Aerosmith) and bridge generation gaps (Santana and Michelle Branch). Here are a few dynamic duos that prove music can bond the most unlikely artists and create some of music's most memorable moments. Feel free to dedicate one to your soul mate.


Ja Rule and Ashanti
"Mesmerize"


Ja Rule and Ashanti show why they're "the ones that we want" in this remake of the final scene from the movie Grease.

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J. Lo and LL Cool J
"All I Have"


In "All That I Have," J Lo and LL Cool J play ex-lovers who can't stop singing into their cell phones.

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Santana and Michelle Branch
"The Game of Love"


22 year-old newcomer Michelle Branch and guitar legend Carlos Santana prove that music can bridge age gaps as steep as theirs on "The Game of Love."

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Kid Rock and Sheryl Crow
"Picture"


A shared passion for lovesick country blues brought this unlikely duo together on the hit "Picture."

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Eve and Gwen Stefani
"Let Me Blow Ya Mind"


Gwen Stefani united with Eve for a night out on the town, blowin' minds and glammin' it up.

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Ozzy Osbourne and Lita Ford
"Close My Eyes Forever"


We don't get to hear Ozzy in this clip, but his super-teased hairdo speaks for itself.

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