Stephenie Meyer's reign as vampire queen at the box office may be coming to an end with the November 16 release of "The Twilight Saga: Breaking Dawn - Part 2," but the author is hardly abandoning the cineplex. In fact, she's planning her next invasion with the help of an army of extra-terrestrials.

"The Host," based on Meyer's best-selling adult novel, hits theaters March 29, 2013, and MTV News has your exclusive first look at the trailer!

Set in a desolate, post-apocalyptic landscape in which most of the human race has been wiped out by invading parasitic aliens known as Souls, the trailer opens with Earthling Jared Howe (Max Irons) confronting an intruder he believes to be one of the enemy, but instead, is Melanie (Saoirse Ronan), a fellow refugee. And, as two of the last humans are wont to do, the pair embark upon a romance. That is, until Melanie is captured by a host of Souls and implanted with alien Wanderer.

But Wanderer is not strong enough to take complete control of Melanie's consciousness, and they are left living in tandem in one body. Melanie soon convinces Wanderer to go in search of love Jared and what's left of her family—set to the pulse-pounding soundtrack of Imagine Dragon's "Radioactive."

MTV News recently spoke with Ronan who's seen an early cut of the finished product, and she was pleased with what she saw. "It's great to just see it all put together and see how it looks and how certain scenes turned out," she said. "There are some nice moments in there. I loved working with everyone on it but I really loved working with William Hurt just because he was a great leader really for all of us. He raised questions that some of us might not have if he wasn't there so it was lovely to see the scenes that we did together."

Co-starring Jake Abel, Diane Kruger and Frances Fisher, "The Host" hits theaters March 29, 2013.

Check out everything we've got on "The Host."