Music mogul and onetime Summer producer Quincy Jones, who worked with the singer during her Donna Summer era, remembered her on Twitter: "Rest in Peace dear Donna Summer. Your voice was the heartbeat and soundtrack of a decade."
Frequent Summer collaborator, producer and musician Nile Rodgers, remembered his pal, writing, "This may help you understand why i'm still crying. So much love and RESPECT for Donna Summer RIP."
RIP Donna Summers!!!!!!!!!😔. You were truly a game changer!!!— Mary J. Blige (@maryjblige) May 17, 2012
R&B diva Mary J. Blige paid homage to her soul sister on Twitter, posting, "RIP Donna Summers!!!!!!!!! You were truly a game changer!!!"
Former Destiny's Child singer Michelle Williams was also floored by the unexpected and tragic passing of the dance-floor icon. "Shocked and saddened at the news of Donna Summer passing away! "she wrote. "Wow!"
Her fellow DC sister, Kelly Rowland, added, "Donna Summer. Icon! Legend! Her voice! Her spirit! Rest In peace, you truly inspired me! I love you!"
Rihanna seemed so surprised by the news, she simply tweeted, "Donna Summer??"
British pop songstress Kylie Minogue, whose own flashy, dance-heavy career can be traced back to Summer's influence, wrote, "One of my earliest musical inspirations, RIP Donna Summer #BadGirlsForEver."
Beyoncé's sister, Solange Knowles, who is known for her throwback style in music and fashion, shared, "Donna Summer- You have inspired me in so many ways....."
this cant be tru tmz.com/2012/05/17/don... i cant believe this RIP Donna Summer. at a lost 4words— Timbaland (@Timbaland) May 17, 2012
Hip-hop producer Timbaland added, "This cant be tru. i cant believe this RIP Donna Summer. at a lost 4words."
Q-Tip reacted to the number of icons who have died already in 2012. "I'm getting tired of these 3 keys...RIP this time to Donna summer an amazing trailblazer!"
Boyz II Men also had a similar reaction on their Twitter: "It's unfortunate that we have to say goodbye to another amazing talent. Donna Summer, Queen of Disco, our condolences to her family!"
"I remember sitting in the front seat of my mom's toyota while she sang Donna Summer's 'she works hard for the money,' " Ryan Seacrest recalled. "Songs were just classic."
Fellow TV personality Carson Daly sent his condolences to her family. "We lost the Queen of Disco today, Donna Summer, 63- another victim of that bastard, cancer. My thoughts and prayers go out to her family."
"In Living Color" actor Tommy Davidson sent MTV News a statement about the singer's passing: "Donna Summer used disco to bring the most unlikely people together -- blacks, whites & everyone in between. Donna was a role model, the consummate professional. Her guidance and inspiration will forever help me reach new heights as a performer. I cherish the days I toured with her. Love to love you, baby."
Other Hollywood folks remembered Summer, including Kevin Smith. "Damn... donna summer dies at 63. An unforgettable voice from my childhood, beloved by my Mom & brother," he tweeted. "Let's dance the last dance for her."
Share your condolences for Donna Summer's friends, family and fans in the comments or on Facebook.