Paul Rudd and Jennifer Aniston are going to leave it all behind for "Wanderlust," but before they do, they're answering your questions.

On Wednesday, February 22, Rudd and Aniston will sit down with MTV News' Josh Horowitz to present a clip from their brand-new movie "Wanderlust" during "MTV First." At 7:56 p.m. ET on MTV, the two will introduce the clip. Immediately afterward, the interview will continue for 30 minutes on MTV.com, where Rudd and Aniston will answer more of your questions.

To get your question answered, all you have to do is send it via Twitter, using @MTVNews and the hashtag #MTVFirst or #AskWanderlust.

"MTV First" will give you a chance to see a never-before-seen clip from "Wanderlust," two days before it hits theaters February 24.

In "Wanderlust," Rudd and Aniston play two down-on-their-luck New Yorkers who look for a new way of life. After first seeking refuge with relatives, the couple stumble across Elysium, a commune of free-spirit people who welcome them with open arms — a little too open.

"Wanderlust" comes from director David Wain and co-writer Ken Marino, two of the guys behind the cult classic "Wet, Hot American Summer," and comedy super-producer Judd Apatow. Justin Theroux and Malin Akerman co-star.

Be sure you get your questions in to MTV.com or via Twitter, using @MTVNews and the hashtag #MTVFirst to get your questions answered by Paul Rudd and Jennifer Aniston. Then tune in to MTV at 7:56 p.m. ET on Wednesday, February 22, to see if your question made the cut.

Check out everything we've got on "Wanderlust."

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