In a race that was considered to be a battle of the A-listers, George Clooney took home the Golden Globe for Best Actor in a Motion Picture - Drama for "The Descendants."

After an evening of joking about his celebrity best bud, George Clooney opened his acceptance speech by letting Brad Pitt know exactly what he thought of him.

"I wanted to say it's nice to see Brad, and it's nice to be able to tell him not just what wonderful work he's doing in two films this year," Clooney said. "But what wonderful work he does in the rest of the world to the rest of the people."

Pitt, who was nominated for "Moneyball," and Clooney emerged as the front-runners in the category soon after the nominees were announced last month, and their well-documented friendship came to dominate the conversation around the race.

Earlier in the evening, Clooney borrowed the cane Pitt used throughout the evening, seemingly to poke fun at his friend.

Clooney also acknowledged one of the actors he got to meet for the awards show, fellow nominee Michael Fassbender, and he took the opportunity to crack a joke about Fassbender's revealing role in "Shame."

"I'd like to thank Michael Fassbender for taking over the frontal-nudity responsibility that I had," Clooney said. "Michael, honestly, you can play golf like this with your hands behind your back. Go for it, man. Do it."

Toward the end of his acceptance speech, Clooney got a little more serious and thanked his co-stars and writer/director Alexander Payne. "Thank you very much to Alexander Payne, who makes wonderful films and is a great friend," he said.

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