Mandy Moore has long bounced between TV, movies and music, and now the "Princess Diaries" co-star is trying her hand at a sitcom. Moore, who has guested on "Scrubs," "Grey's Anatomy" and "American Dreamz" in the past, will star in the new single-camera sitcom "Us and Them," according to The Hollywood Reporter.

The family comedy is described as the story of the "inherent conflict that exists between the families you grow up in and the ones we make as adults," told through the perspective of Moore's newlywed character Anne and her husband, Ben. Among the producers on the show are Jon Leshay, who was a music supervisor on a number of Moore movies, including "Saved!," "How to Deal" and "A Walk to Remember."

"Night at the Museum" director Shawn Levy will direct and executive-produce the show. Moore voiced the lead character in last fall's animated Rapunzel tale "Tangled" and appeared on this year's Academy Awards broadcast singing the Oscar-nominated tune from the movie, "I See the Light."

While her music career has been on hold since 2009's Amanda Leigh, husband Ryan Adams has just released his 13th studio album, Ashes & Fire, on which she sings backing vocals on the song "Come Home."

Moore is also slated to appear alongside the voices of Elijah Wood, Lance Henriksen and "Entourage" star Emmanuelle Chriqui on the upcoming animated TV series "Tron: Uprising," which is slated to air on Disney XD next summer. She will voice the character Mara in the show, which takes place between the time of the original film and last December's re-boot, "Tron: Legacy."