Katy Perry is making her big-screen debut as the voice of Smurfette in "The Smurfs," out Friday. She brings her kooky cool personality to her role as the sole female in Smurf Village. Her "Smurfs" co-stars were happy to congratulate Perry on another big milestone she will be celebrating four weeks from now, when she'll attend the 2011 VMAs as the most-nominated artist of the year.

"Katy Perry can do no wrong in my book," Neil Patrick Harris gushed to MTV News. "She's tall, she's funny, she can sing and has a sharp wit and is a savvy businesswoman. I say Katy Perry may take over the world. I will be her vice president."

Hank Azaria, who plays bad guy Gargamel in the partially animated, 3-D romp, had similar sentiments for the larger-than-life pop star, though he actually just met her for the first time at the movie's premiere. "Congratulations, Katy Perry/Smurfette," he said, before admitting, "I'm just not up on the young people's music of today. I've heard of her [and] the fact that I know who she is is tremendous, because if I know who she is, and she's a recording artist under the age of 35, that means she's very big."

So, what kind of impression did Perry leave on Azaria? "It was rather exciting," he said. "She's a genuine pop idol; my heart raced. She's beautiful and a huge star."

Perry will be competing for Video of the Year and Best Female Video for "Firework"; Best Pop Video for "Last Friday Night (T.G.I.F.)"; and Best Collaboration, Best Art Direction, Best Direction, Best Editing and Best Special Effects for the Floria Sigismondi-directed "E.T.," which features fellow nominee Kanye West. Her "Teenage Dream" clip also nabbed a nomination for Best Cinematography.

The 28th annual MTV Video Music Awards will air live on Sunday, August 28, from the Nokia Theatre in Los Angeles at 9 p.m. ET/PT. See the list of nominees, revisit last year's highlights and vote for your favorites in the general categories by visiting VMA.MTV.com.