From the very first time Jake Gyllenhaal and Anne Hathaway meet onscreen in "Love & Other Drugs," clothes come off and a whole lot of skin is exposed. That nude scene sets the tone for the rest of the film, surprising in that these two A-listers seem to bare it all at nearly every turn.

"I don't think there's anything wrong with nudity in film, and I would hope that any actor that is asked to reveal that part of themselves has as loving and open an experience as we had," Hathaway recently told MTV News.

Gyllenhaal clearly agreed and he was more than happy to let Hathaway explain the rather unique experience they had with their nude scenes in the movie opening November 24. "You're good at this one!" he said.

The usual protocol for nude scenes in Hollywood is for filmmakers to prepare a comprehensive outline of exactly what body parts will be exposed onscreen. Then the negotiations begin. That's not what happened between Gyllenhaal, Hathaway and director Edward Zwick on "Other Drugs," a film about a charismatic Viagra salesman (Gyllenhaal) who falls for a free-spirited beauty with one dark secret (Hathaway).

"We just kind of all decided to go a different way this time," Hathaway explained. "[Jake and I] talked about it and we talked with Ed about it and we said, 'You know, we're gonna do what we feel comfortable. Let's talk about why we feel this is important. Let's talk about the story we hope to tell through these scenes.' I think there's a big difference between having nudity and having two characters living their lives without their clothes on.

"Then once we kind of decided how we feel about it, we said, 'Ed, please shoot it as you see fit,' knowing that Ed is not an exploitative person," she continued. "And at the end, we were shown the scenes that Ed had cut and we were given full license to say, 'I don't like this, I do like this, I think this shot feels a little linger-y to me.' As a result, it became this organic process."

What do you think of Hollywood stars baring skin on the big screen? Tell us in the comments!

Check out everything we've got on "Love & Other Drugs."

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