Since hitting the stage at last year's show, where she took home a prize, hit the carpet with Kermit the Frog, got bloody onstage and had multiple wardrobe changes, Gaga has established herself as one of the music industry's biggest stars, thanks to the success of her album The Fame and her love for her "little monsters."
Shortly after the VMAs last year, Gaga ditched a planned tour with awards-show rabble-rouser Kanye West, calling the decision "mutual" and opting to go on a solo outing instead. In November, she released The Fame Monster and the epic "Video Phone" clip, telling Beyoncé for the Hype Williams video: "I want to tribute you."
Around the same time in November, Gaga released her VMA-nominated video for "Bad Romance." The eye-catching video, directed by Francis Lawrence, kicked off a string of Gaga videos that would leave fans' minds boggled and hungry for more Gaga-fied visuals.
In January, Gaga took home some Grammys and performed at the show alongside piano-pop god Elton John, wearing what looked like a planet to the event. That same month, Gaga raised $500,000 for Haitian earthquake relief.
March saw Gaga get very, very ambitious, with the release of her massive video for "Telephone" with Beyoncé. And while the director, Jonas Åkerlund, said the clip had nothing to do with "Kill Bill," its Tarantino-esque touches certainly had fans watching over and over again.
Lady Gaga hit the "American Idol" stage to perform her track "Alejandro," and in June, she released a video for the summer-friendly track, complete with Madonna references and a Katy Perry beef. (The Perry beef was one of many in 2010; she also found herself criticized by Christina Aguilera, M.I.A. and Beatles fans.)
June also saw Gaga acting out at baseball games and revealing that her next album was basically done. She later debuted the new track "You And I" at an Elton John benefit. While she may have the most Twitter followers, for a short time in July, Justin Bieber had more YouTube streams.
This year, three of her tracks — "Bad Romance" and "Telephone" and "Video Phone" with Beyoncé — rule the VMA nominations. Which Moonmen will she win? More importantly, what will she wear? It's only a matter of time until we find out.
The 27th annual MTV Video Music Awards will be broadcast live from the Nokia Theatre in Los Angeles on September 12 at 9 p.m. ET.