"Our team simply chose to move on from Lindsay and we'll soon be announcing a replacement," David Michaels, the writer/director of the film, told TMZ.
Sources close to the production say that the financial backers of the flick had reservations about Lohan's casting. However, USmagazine.com reports that financing difficulties for the film weren't connected to Lohan and that it had "nothing to do with Lindsay. It was because it was an unknown director. All the major stars in this film dropped out."
The film once reportedly had the late Brittany Murphy attached to it, and currently lists Woody Harrelson, Giovanni Ribisi, Dave Matthews and Alanis Morissette in its cast. Lohan would have reportedly played a grad student working on a deserted island.
Lohan will next appear in the Robert Rodriguez-directed flick "Machete." She was recently in India shooting a documentary about human trafficking for the BBC, and last summer she starred in the ABC Family flick "Labor Pains." Lohan's rep hadn't responded to MTV News' request for comment on the firing by press time.
In the past, Lohan has spoken publicly about her problems in Hollywood, noting that it's been hard for people to give her a second chance. "There's not much I can do about the fact that I've become a kind of tabloid obsession," she said. "I can't change that. And yes, the Web sites, the gossip pages, and all of that stuff have hurt my career — they're like the Burn Books of Hollywood."
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