The performance started with Wayne, wearing a white jacket and white T-shirt that read "Listen to Lil Wayne," spitting his opening verse from "Drop the World."
"I got ice in my veins, blood in my eyes/ Hate in my heart, love on my mind/ I seen nights full of pain, days of the same/ You keep the sunshine, save me the rain."
After his verse and chorus, Eminem walked onstage to audio problems — his live vocals were inaudible over the track. Slim Shady — who filmed the video to the song Saturday with Wayne — kicked in with his rapid-fire flow just as the mic began to work again.
A live band, which included Blink-182's Travis Barker on drums, backed the MCs. When the beat changed to "Forever," Drake joined the crew while Wayne and Em hyped in the background.
The studio version of "Forever" also features Kanye West, but he didn't make it to the awards show. Drake said before the show that 'Ye was in a "creative space." On Friday, Travis Barker didn't offer much more in the way of details.
"I don't know," he said about West's whereabouts. "Someone said he's in Hawaii writing an album. I would stay there."
West's friends and musical collaborators have been tweeting that Kanye is working on an "inspiring" new album.
The 2010 Grammy Awards may be over, but MTV News will have much, much more from the show, including reports on your favorite nominees, party photos, behind-the-scenes video and much more from the big show!