Alicia Keys is heading to Cape Town, while Missy Elliott and Dave Matthews will take over Seattle for two separate performances that will be edited together for a concert special to air on World AIDS Day December 1.

The concerts, announced Thursday (October 3), will be combined as a commercial-free, 90-minute program and aired globally on MTV to an anticipated world audience of 2 billion people. In addition to the television broadcast, Westwood One's radio network will distribute the concert to radio stations worldwide.

The programming is part of MTV's yearlong sexual health campaign, Fight for Your Rights: Protect Yourself.

"With more than 50 percent of all new HIV/AIDS infections occurring among people under the age of 25 around the world, this disease is reaching crisis proportions among young people globally. The good news is, that through education, awareness and diligence, this disease is wholly preventable," MTV President of Entertainment Brian Graden said in a statement.

The Seattle concert will take place at Experience Music Project on November 7. The Cape Town concert will be held at Greenpoint Stadium on November 23. More acts remain to be announced for both. MTV Presents Levi's Jeans Staying Alive Concert airs December 1.

The concerts are made possible by a partnership of business, media and charitable organizations, including Levi's, the Bill & Melinda Gates Foundation, the Paul G. Allen Charitable Foundation, the nonprofit organization Population Services International's YouthAIDS and UNAIDS (the joint United Nations program on HIV/AIDS).