It might sound strange, but it's true: Reese Witherspoon kicked the crap out of Jackie Chan. Twice, even.

Witherspoon's "Sweet Home Alabama" beat out Jackie Chan's "The Tuxedo" for the top spot at the box office over the weekend while also overtaking "Rush Hour" to become the biggest September opening of all time. (Click for photos from "Sweet Home Alabama.")

Witherspoon's latest star vehicle, a romantic comedy costarring Patrick Dempsey ("Scream 3") and Josh Lucas ("A Beautiful Mind"), took in $37.5 million in its opening weekend, according to studio estimates released on Sunday, $4.5 million more than Chan's "Rush Hour" opened with in 1998. "The Tuxedo," an action/comedy starring the veteran martial arts star alongside Jennifer Love Hewitt ("I Know What You Did Last Summer"), took the #2 spot with $15.1 million.

"Sweet Home Alabama" also broke another record. Julia Roberts' "Runaway Bride" previously held the top opening spot for a romantic comedy with the $35.1 million it earned in July 1997. Only two other female star-led movies — "Charlie's Angels" and "Lara Croft: Tomb Raider" — made more on their opening weekends than "Sweet Home Alabama."

Despite renewed interest caused by recent controversy (see " 'Barbershop' Attacked By Reverend Jesse Jackson"), Ice Cube's ensemble comedy "Barbershop" relinquished the top spot it had held for two weeks (see "Moviegoers Find Haircutting More Interesting Than Spies, Groupies, Kidnapping, War") and moved down to #3 with $10.1 million, for an overall take of $51.4 million.

The rest of the weekend's top 10 includes "My Big Fat Greek Wedding" at #4 with $9.7 million ($136.9 million over 24 weeks); Goldie Hawn/ Susan Sarandon groupie flick "The Banger Sisters" at #5 with $5.4 million ($18.8 million, two weeks); "The Four Feathers" at #6 with $3.6 million ($12.4 million, two weeks); Robin Williams' "One Hour Photo" at #7 with $3 million ($26 million, six weeks); "Ballistic: Ecks Vs. Sever" at #8 with $2.6 million ($11.5 million, two weeks); "Signs" at #9 with $2.3 million ($221.1 million, nine weeks); and "Swimfan" at #10 with $1.5 million ($26.6 million, four weeks).