'Machete Kills' Trailer Will Slay You, Son

Robert Rodriguez is clearly one sick and twisted film-making individual, but hey, it works.

The first trailer for his "Machete" follow-up titled "Machete Kills" is in, and it basically operates as a virtual Who's Who of the most oddball cats in Tinseltown.

Joining Danny Trejo for movie two of the "Grindhouse" spin-off series — which, let that seep in for just a second — are a bevy of randoms from across the entertainment biz spectrum, including Charlie Sheen, Lady Gaga, Mel Gibson, Vanessa Hudgens, Demian Bichir, Sofia Vergara, Antonio Banderas, Alexa Vega, Amber Heard, Michelle Rodriguez, Cuba Gooding Jr. and, reprising her resident hot chick role, Jessica Alba. That's, uh, quite the spread he's got for this bloody display.

And, naturally, there are some pretty awesome little highlights to parse through here. First, we were particularly amused by this bit with Carlos Estevez Charlie Sheen as one take-no-names POTUS instructing someone off screen, "Let's go kick some a**" while ditching his nerdy specs ...

Charlie Sheen in Machete Kills Trailer Gif

... and we really got a kick outta whatever was happening with Sofia Vergara's gun bosoms in this frame ...

Sofia Vergara's gun bra in Machete Kills Trailer GIF

... also, there was this bit with Lady Gaga, ever the flamboyant femme fatale, hailing down a trucker in stilettos and fur for some reason ...

Lady Gaga Machete Kills trailer GIF

... but most of all, we were totally owned once they showed us Mel Gibson doing machete stuff because c'mon.

Mel Gibson in Machete Kills trailer GIF

You know what they say: go big or go home! (Or just go to the theaters on Sept. 13 to catch this bad boy on opening day.)