Anne Hathaway and Bradley Cooper Nuts for Each Other in 'The Silver Linings Playbook'

[caption id="attachment_22042" align="alignleft" width="300" caption="Getty Images"]Bradley Cooper and Anne Hathaway[/caption]

It seems Anne Hathaway is making a career out of playing women who aren't exactly the picture of health.

After portraying a quirky gal battling Parkinson's disease in "Love and Other Drugs," Hathaway, 28, is now set to star as a quirky gal battling mental illness in "The Silver Linings Playbook."

The film, which will be helmed by David O. Russell, is based on Matthew Quick's novel of the same name, according to Russell is reportedly eyeing "The Hangover 2" star Bradley Cooper, 35, as the male lead, a high school history teacher released from a mental hospital and placed in his mother's care. Though Cooper's character aims to win back his ex-wife, he ends up falling crazy in love with Hathaway.

Before going nuts over Cooper, Hathaway will team up with actor James Franco to co-host the Oscars on February 27. And judging by a recent Vulture interview, the actress will have no problem playing a lovable loony. When the writer joked that she get a fake arm and pretend to tear off "127 Hours" star Franco's limb during the opening monologue, she was more than game – except for one minor detail.

"Fake arm?" she asked. "No way!"