On behalf of the Raiola family, close friend Vinnie Medugno confirmed the news that the larger-than-life Staten Island reality star had "peacefully ended her battle with cancer" with a statement on Big Ang's Twitter account. The Mob Wives star was being treated for stage 4 lung and brain cancer at the time of her passing.
"YOU (fans) were some of the most special people in her world, and she loved you immensely," the statement read. "Thank you for your love, prayers, and unconditional support of Angela right to the end."
In March 2015, Raiola underwent a procedure to remove a "lemon-sized" tumor from her throat. Three months later, she underwent the same procedure for the right side of her throat, and in December, it was revealed that her cancer had returned and spread to her brain and right lung.
"It's shocking what happened," Big Ang shared on the February 16 episode of The Dr. Oz Show. "First I thought I was cancer-free. I was gonna have a big celebration... and then a month later I was stage 4."
Earlier this week, Raiola announced that she and her husband of six years, Neil Murphy, had separated because she felt like he had "never stepped up to the plate."
"So I was done with it," she told The Dr. Oz Show. "I feel now it's too late. Bye. I rather be by myself."
Known for her boisterous personality and crazy onscreen antics, Big Ang also had an incredible bond with her family -- her "inner circle."
"We're a very tight family," she said. "If my family wasn't here to support me through all this, I don't think I could do it."
Raiola is survived by her sister, Janine Detore, her two children, Raquel and Anthony Donfrio, and six grandchildren. Her youngest grandchild, Anjolie Scotto, was born three weeks ago. "This little bundle of joy is what makes it all worth while," Raiola posted on her Instagram page.
We'll miss you and your big heart, Ang.