MTV's Musical March Madness: Panic! At The Disco Vs. Florence And The Machine

It's MTV's second annual Musical March Madness! MTV News took the 64 biggest names in rock, split them up into four regions, assigned them seeds and puts them up against one another in a single-elimination series of match-ups in a winner-take-all contest. We're leaving it to you to decide an actual champ in this field of 64, so over the next few weeks, fan voting will determine who will emerge as this year's champion. It's all about the fans, and the artist with the most passionate fan base will score the awesome Musical March Madness trophy!

The games in the NCAA men's basketball tournament don't start up again until Thursday (March 24), but the throwdowns in MTV's Musical March Madness continue unabated. Check out the next pairing from the West bracket, which pits a couple of young superstars against one another.

Voting for all second round match-ups will close on Sunday, March 27 at midnight. As always, you can follow all the voting here.

(4) Florence and the Machine vs. (5) Panic! at the Disco

Panic! at the Disco are one of the favorites in this year's tournament, and they established themselves as serious contenders in their first round victory over a game Avril Lavigne. They have to overcome a spry Florence and the Machine squad that trounced Brandon Flowers in round one. Will they play spoiler, or will Panic! at the Disco ride their just-released new album Vices & Virtues to the Sweet 16? You decide!

Watch the breakdown of the first round and a preview of round two!


Check out the Musical March Madness bracket and be take a look at the hoops-centric photos of some of the tournament's biggest bands.