MTV's Musical March Madness: Coheed And Cambria Vs. Vampire Weekend

It's MTV's second annual Musical March Madness! MTV News took the 64 biggest names in rock, split them up into four regions, assigned them seeds and puts them up against one another in a single-elimination series of match-ups in a winner-take-all contest. We're leaving it to you to decide an actual champ in this field of 64, so over the next few weeks, fan voting will determine who will emerge as this year's champion. It's all about the fans, and the artist with the most passionate fan base will score the awesome Musical March Madness trophy!

We're half way through the first bracket of the second round of MTV's Musical March Madness tournament. In this match-up, the defending champs Coheed and Cambria take on indie favorites Vampire Weekend in what should be an intriguing confrontation.

Voting for all second round match-ups will close on Sunday, March 27 at midnight. As always, you can follow all the voting here.

(3) Vampire Weekend vs. (6) Coheed and Cambria

Coheed and Cambria won the 2010 MTV Musical March Madness championship, and they kicked off the first round of this year's tournament the same way they tore through last year's: by trouncing the competition (this time around, the victim was "American Idol" veteran Crystal Bowersox). In round two, they go head-to-head against Vampire Weekend, who topped fellow indie icons Bright Eyes to advance. Will Coheed make another trip to the Sweet 16, or will Vampire Weekend be the band who finally spoils their dance? Vote and find out!

Watch the breakdown of the first round and a preview of round two!


Check out the Musical March Madness bracket and be take a look at the hoops-centric photos of some of the tournament's biggest bands.