Stars Prepare To 'Stand Up To Cancer' In Today's Tweet Dreams

Standing up to cancer is an effort that takes a lot of work from a lot of people, which is where the "Stand Up To Cancer (SU2C)" show comes in to lend more helping hands. Tonight, an hour-long, commercial-free telecast will air on television and online, featuring some of Hollywood's biggest names, to help raise awareness and donations for a most worthy cause (the evening feels especially poignant in the days following the passing of Rich Cronin.) Late night TV host Jimmy Fallon shared with followers his reasons for participating, "I #StandUp2Cancer in honor of my grandparents. Watch SU2C tonight on every network and at Thanks."

Celebs who have faced cancer head-on are also joining the SU2C fight, including "Survivor" star Ethan Zohn, who tweeted, "Tune in to join me in the years biggest tv event! Join me and #StandUp2Cancer on September 10 at 8pm ET/PT, 7pm CT." Breast cancer survivor Christina Applegate (pictured) informed fans, "Tune in to Stand Up To Cancer tonight 8pm EST/PST on all major networks.I am in the opening, then will be answering phones!"

"Stand Up To Cancer (SU2C)" begins tonight at 8 p.m., check local listings for networks.

Check out the rest of Friday's best tweets from the stars, including "The Situation" gearing up for this weekend's VMAs and his upcoming stint on "Dancing With the Stars" and Jane Lynch's guest spot on "iCarly"! Follow us @hollywoodcrush to get even more celebrity and pop culture news around the clock!

@peterfacinelli Woke up in a hotel this morning and it took me five minutes to figure out where I was. #thatsChicago

-Peter Facinelli, Actor ("Eclipse," "New Moon")

@itsthesituation Finally home , but not for too long , going to LA tomorr for VMA's n then putting my dancing shoes on for DWTS

-"The Situation," Reality Star ("Jersey Shore")

@themandymoore Starting my day by blasting my hubby's bad-ass III/IV record. Hell yah!

-Mandy Moore, Singer, Actress ("A Walk To Remember")

@mirandabuzz Jane Lynch guest stars as Sam's Mom tomorrow night! After 70 episodes it's finally here!

-Miranda Cosgrove, Singer, Actress ("iCarly," "Despicable Me")

@shaymitch Just wrapped another great day on set of Pretty Little Liars... #trulyblessed

-Shay Mitchell, Actress ("Pretty Little Liars")

@mindykaling Supervising gory blood spatters on set. It's not Dexter, it's not True Blood, it's The Office.

-Mindy Kaling, Writer, Actress ("The Office")

@davidspade the good news: brad pitt is shooting a movie in stage next to mine. The bad news: 3 people thought i was Shilo

-David Spade, Comedian, Actor ("Grown Ups")

@heyitsnicolea I want to be apart of the Pinkett-Smith family. They're producing talent up the wahoo.

-Nicole Anderson, Actress ("Mean Girls 2," "JONAS L.A.")

@katyperry What ever happened to Jonathan Taylor Thomas #teenagedream

-Katy Perry, Singer

@markhoppus My football season prediction: this year, one of the teams in the NFL will win the SuperBowl. You're welcome.

-Mark Hoppus, Musician (blink182)

Movie & TV Awards 2018