As we've all learned from her star-making turns in "Bridesmaids," "Neighbors," "Get Him to the Greek" and more, Rose Byrne knows how to dole out some sick-ass burns. So sick, in fact, that they once drove Kristen Wiig to madness, broke Russell Brand's heart, and even broke up Zac Efron's iron-clad relationship with his girlfriend. I mean, that's a sure sign of a great Byrne-Burn.
Check out some of our favorites below:
The poor people Byrne-Burn.
Sick burn, Byrne!
The "I'm stealing your girlfriend" Byrne-Burn.
Good one, Byrne!
The angry mama Byrne-Burn
Protect those kids, Byrne.
The insulting your car Byrne-Burn.
A subtle yet effective Byrne.
The "you're boring me, get me more alcohol" Byrne-Burn.
Use them servants, Byrne.
The passive aggressively insulting your BFF Byrne-Burn.
Maya Rudolph is spoken for, Byrne.
The "I don't care what you think about me" Byrne-Burn.
Let it roll off those shoulders, Byrne.
The fashionable Byrne-Burn.
Melissa McCarthy finds out the hard way in this exclusive clip from "Spy" that one is never truly safe from a Byrne-Burn.