Filming a Western probably isn't as bad as actually being in the Old West, but sometimes, it might come close.
"The weather was a nightmare," MacFarlane said. "If you're doing a Wetern and you want to capture vistas like this, Monument Valley, that's an unfortunate part of the process."
"There were dust storms," Sarah Silverman added. Sometimes it got so bad that co-star Giovanni Ribisi would shout to her, "Sarah, I can't see you!"
One scene in particular was torturous to film, especially for one person in particular.
"That one funeral scene... that was so cold that night," Silverman said. "And there was an old lady extra, and like, we get warming jackets in between, and I felt so bad. So I was like 'come into my jacket.'"
Silverman wryly added, "Too bad you're not talent."
And MacFarlane's favorite awful part? "I love crawling through sheep s--t."
With the dust storms, the cold, and the animal excrement, was it really worth going through all that trouble to make the movie?
"It is worth it, it looks gorgeous," MacFarlane said. "People have said, 'Oh the movie looks expensive,' and it's really not an expensive film."
We hope for MacFarlane's actors' sakes that the funnyman's next movie is set in Hawaii.
"A Million Ways To Die In The West" is in theaters now.