And unless you want to miss Wilson crashing into the Sony Pictures Studios lot — or the highly anticipated "Pitch Perfect" performance to follow — you best be in your seat by 9 p.m. ET.
What's more, we've got the secret skinny on the evening's not-to-be missed mash-up, conceived by director Jason Moore and featuring Wilson with co-stars Skylar Astin, Anna Camp, Ester Dean, Alexis Knapp, Hana Mae Lee, Ben Platt, Brittany Snow and Utkarsh Ambudkar.
"We have something exciting in store for the MTV audience, and I know the cast and the fans are going to really enjoy our first-ever live performance!" Moore said.
And here it is: The reunited Barden Bellas and Treblemakers are set to put their own aca-twist on Miley Cyrus' "The Climb," Eminem's "Lose Yourself," Alicia Keys' "Girl on Fire" and Macklemore & Ryan Lewis' "Thrift Shop." (The hip-hop duo will be well-represented at the awards show, as they'll take the stage later in the evening for a performance of their latest single "Can't Hold Us.")
And as Skylar Astin revealed earlier in the week when we snuck into a top-secret performance rehearsal, you can expect a lot more than just singing from the troupe.
"There's explosions. There's Rebel," he said. "Every part is very important, and it's important to pay respect and understand what's going on around you."
The first-act highlights don't end there: Following all that a cappella, "The Heat" star Melissa McCarthy will take the stage to present the Best Male Performance Golden Popcorn to one of these lucky men: Ben Affleck ("Argo"), Bradley Cooper ("Silver Linings Playbook"), Channing Tatum ("Magic Mike"), Daniel Day-Lewis ("Lincoln") or Jamie Foxx ("Django Unchained").
It all goes down during the MTV Movie Awards' opening minutes, so tune in on time at 9 p.m. ET so you don't miss a moment.