Lady Gaga has some news for all her Little Monsters. The Mother Monster herself will sit down with MTV News and Sway Calloway on Thursday night (August 18) during "MTV First: Lady Gaga" to premiere her highly anticipated music video for "Yoü and I." And during her live interview, she's also set to make another big announcement.

After the video premieres at 7:49 p.m. ET on MTV and Logo, it will appear on mtvU, MTV Hits and Tr3s at 8 p.m. on Thursday. And immediately following the on-air portion, Gaga's interview and fan Q&A will stream live on MTV.com.

Want to get in on the fun? Submit questions beginning Monday (August 15) via Twitter using the hashtag #MTVGaga.

"Yoü and I" is the fourth video off of Gaga's chart-topping Born This Way. She's already dazzled fans with high-concept clips for "Born This Way" and "Judas" and then kicked it more lo-fi and old school in her video for "The Edge of Glory," which co-starred the late Clarence Clemons.

Gaga promised fans that she'll post a link to the video as her 1,000th tweet. So far she's posted several hints about the video as she approaches that number. Tweet #993 reads, "Love is a Result. We bare an Unbearable Human Inability: to just 'be.' " It also features a photo of a woman, presumably Gaga, in a white dress, sitting at a piano in the woods. Her next two tweets hinted that the premiere would take place in "Less than a week" and then the accompanying photo was of dirty feet in high-heeled platforms.

[article id="1668367"]Go behind the scenes of a top-secret Lady Gaga shoot.[/article]

Last week [article id="1668621"]Gaga tweeted out single artwork for "Yoü and I,"[/article] which featured her male alter-ego, Jo Calderone. Gaga previously teased that the video would include another one of her alter egos, that of her [article id="1667045"]mermaid incarnation, Yuyi[/article].

[article id="1667921"]Gaga shot the video[/article] in Nebraska last month and explained that it is about taking a journey to win back the one you love. "The [video is about the] idea that when you're away from someone you love, it's torture," she said. "I knew I wanted the video to be about me sprinting back and walking hundreds of thousands of miles to get him back."

Don't miss the premiere of the "Yoü and I" video during "MTV First: Lady Gaga," Thursday night at 7:49 p.m. ET on MTV and Logo, followed by a live Q&A with Gaga and her fans on MTV.com. Tweet your questions for the Mother Monster with the hashtag #MTVGaga.