Nick Cannon Twitter Tirade Attacks Chelsea Handler

Handler's lighthearted opening shot incites Cannon to fire back with a vengeance.

There seems to be a beef brewing between Nick Cannon and late-night comedian Chelsea Handler. The funny lady used Twitter to take a lighthearted jab at Cannon,

target="_blank">writing, "I just heard nick cannon is starting a comedy tour. Who's going to do the comedy?"

It seems Cannon didn't find the comment humorous.

And it seems with that simple tweet, she struck quite a nerve, because from there, Cannon went on an assault against Handler via his own Twitter.

He kicked it off by saying, "Wow @chelseahandler I actually used to have respect for you as a comic. But for one artist to diss another in the same art form. #Tasteless," he tweeted. "Soon as I get off stage tonight, I'm going in on @chelseahandler I'm about to be relentless!

OFF WITH HER HEAD but right now I got to focus."

From there, his tweets began to escalate. "Okay just left the gotham comedy club in NY, STANDING OVATION! Back tomorrow night! Now let's address this @chelseahandler negativity..." he tweeted late Thursday night. "B4 we get to the jokes @chelseahandler ... All Comics, on sum real sh--, Isn't it comedy 101 that one comic never heckles another comic? Funny how all of @chelseahandler fans are coming at my like I did something to her. I don't even know this broad! She on my sh--!

Comics don't heckles comics that's like a Pimp snitching on a Pimp!"

Then, Cannon started in with personal attacks on Handler:

"@chelseahandler But since it's all in fun and supposedly just comedy, Let's get to the mutha----in' JOKES!! Everyone knows @Chelseahandler had sex with the head of E! for her show. So when its canceled does he get residual pu--- for the reruns. @chelseahandler Looks like she got hit in the face with a hot bag nickels!"

Aside from her appearance and her past dating history, Cannon began tweeting and addressing rumors that the one-time VMA host and 50 Cent are dating. "Just talked to @50cent He said he made @chelseahandler get G-Unit tattooed on her balls!" Cannon wrote. "@50cent wasn't hitting @chelseahandler they was just sharing testosterone tips. @Chelseahandler @Howardstern @Eminem Why do all these angry ugly whitetrash folks want beef with me? What I do? I'm a harmless corny dude!

"@chelseahandler is like the new @joanrivers just without the funny and more plastic surgery."

For Handler's part, she didn't address Cannon after his onslaught of tweets about her, but did joke, "I announce my pregnancy on tonight's show."

This isn't Cannon's first Twitter beef. He famously slung tweets Eminem's way after the MC and Cannon's wife, Mariah Carey, seemingly traded barbs in songs.

Recently, Cannon revived the beef on his blog.

Are you on Handler's side or Cannon's? Tell us in the comments below!