The outspoken actress saw years of hard work pay off when she took home the Best Supporting Actress Oscar for her groundbreaking performance as an abusive mother in "Precious: Based on the Novel 'Push' by Sapphire." Just like when Will Smith, Denzel Washington and Halle Berry took home Hollywood's most coveted prize, Mo'Nique's shining moment was celebrated throughout the hip-hop community.
"Go Mo go!!!" Diddy wrote on Twitter. "Congrats!!!! Let's go!"
"CONGRATULATIONS MoNIQUE!!!!!!!!!!!!!!!!!!" Nicki Minaj tweeted.
"From Soul Plane to winning an Oscar!" radio personality Ed Lover marveled on Twitter. "Congrats Mo'Nique! We are soo proud of you!"
"I'm glad Mo'Nique won," Q-Tip added. "She's a cool down to earth woman."
"Congratulations Monique!" Soulja Boy Tell'em wrote. "You are a queen."
But Mo'Nique's big night wasn't just about her win. Her emotional acceptance speech brought the audience at the Kodak Theatre to their feet.
"I would like to thank the Academy for showing that it can be about the performance and not the politics," Mo'Nique said. "To my amazing husband, Sidney — thank you for showing me that sometimes you have to forego doing what's popular, in order to do what's right."
Relive all the best moments from the 2010 Academy Awards with photos, interviews, blogs, post-show analysis and more, right here at MTV News.