| Year | Movie | Award | Category | |||
| 2008 | Two and a Half Men [TV Series] | Academy of Television Arts and Sciences | Outstanding Lead Actor in a Comedy Series | |||
| 2007 | Two and a Half Men [TV Series] | Academy of Television Arts and Sciences | Outstanding Lead Actor in a Comedy Series | |||
| 2006 | Two and a Half Men: Season 03 | Academy of Television Arts and Sciences | Best Lead Actor in a Comedy Series | |||
| 2005 | Two and a Half Men [TV Series] | Hollywood Foreign Press Association | Best Performance by an Actor in a Television Series - Musical or | |||
| 2001 | Spin City [TV Series] | Hollywood Foreign Press Association | Best Performance by an Actor in a Television Series - Musical or |