Robert John Burke (Robocop/Alex J. Murphy)
Nancy Allen (Anne Lewis)
Rip Torn (Merritt W. Morton-CEO)
John Castle (McDaggett)
Shane Black (Donnelly)
Doug Yasuda (Kanemitsu's Aide)
Bradley Whitford (Fleck)
Daniel Von Bargen (Moreno)
Curtis Taylor (Rehab #1)
Ken Strong (Rehab Patrol)
Stephen Root (Coontz)
Lonnie Smith (1st Rehab at Hotel)
Beth Burns (Teen Prostitute)
John Nesci (Jensen)
Judson Vaughn (Seitz)
Rick Seaman (Rehab Driver)
Mark Gordon (Teckie in Robochamber)
Michael H. Moss (Unfortunate Rehab)
Alex Van (Rehab in War Room)
S.D. Nemeth (Bixby Snyder)
Randy Randolph (Cop in Donut Shop)
John Posey (Nikko's Dad)
Angie Bolling (Ellen Murphy)
Edith Ivey (Elderly Woman in Bathrobe)
Lee Arenberg (Hold-Up Man)
Jeff Garlin (Donut Jerk)
Wilbur Fitzgerald (Rebel with Weapons Cart)
Eddie Billups (Man at Banking Desk)
David de Vries (Informative Yuppie)
Diane Butler (Woman on Vidphone)
Gary Bullock (Gas Station Clerk)
Steve Jacobs (Actor/Actress)
Jodi Long (Nikko's Mom)
Felton Perry (Johnson)
Mako (Kanemitsu)
Jill Hennessy (Dr. Marie Lazarus)
Mario Machado (Casey Wong)
James Lorinz (Upset Driver)
Ron Leggett (Pimp)
Eva La Rue (Debbie Dix)
Ken Jones (Splatterpunk #2)
Bruce Locke (Otomo)
Stanley Anderson (Zack)
CCH Pounder (Bertha)
Robert DoQui (Sergeant Reed)
Remy Ryan (Nikko)