In this suspense story (released as part of Universal's "Inner Sanctum" series, named for the popular radio series of the day), Jeff Carter is a scientist who is working on a medicine which would cure the flu. Carter's duplicitous boss Roger Graham (J. Carrol Naish) sends him on a business trip to South America, and uses his absence to steal Carter's uncompleted formula, as well as the affections of his wife Mary (Brenda Joyce). When Carter returns home and discovers what Graham has done, he plots a grisly revenge. Strange Confession was a remake of the 1934 Claude Rains vehicle The Man Who Reclaimed His Head. ~ Mark Deming, All Movie Guide