Ron Perlman (Hellboy)
John Hurt (Prof. Trevor "Broom" Bruttenholm)
Selma Blair (Liz Sherman)
Rupert Evans (Agent John Myers)
Karel Roden (Grigori Rasputin)
Jeffrey Tambor (Dr. Tom Manning)
Doug Jones (Abe Sapien)
David Hyde Pierce (Abe Sapien)
Andrea Miltner (Doctor Marsh)
Emilio Navarro (kid)
Alvaro Navarro (kid)
Bettina Ask (kid)
Daniel Aarsman (Kid)
Petr Sekanina (German Scientists)
Bridget Hodson (Ilsa)
Jo Eastwood (Down's Patient)
Charles Grisham (Museum Guard)
Mille Wilkie (Young Liz)
Ales Kosnar (German Scientists)
Justin Svoboda (Young Guy)
Winter Ave Zoli (Girlfriend)
Albert May (Train Driver)
Santiago Segura (Train Driver)
Rory Copus (kid on rooftop)
William Hoyland (Von Krupt)
Bob Sherman (Television host)
Guillermo del Toro (Baby Hellboy/Kroenen/Samuel)
Jeremy Zimmerman (lobby guard)
Tara Hugo (Doctor Jenkins)
Mark Taylor (Truck Driver)
Jan Holicek (museum guard)
Pavel Cajzl (Sherpa Guide)
Monty L. Simons (orderly)
Richard Haas (Second Doctor)
John William Johnson (Agent Clay)
Andrea Stuart (Girl with Kittens)
Ellen Savaria (Blonde Television Reporter)
Biddy Hodson (Ilsa)
Corey Johnson (Agent Clay)
Kevin Trainor (Young Broom)
Brian Caspe (Agent Lime)
James Babson (Agent Moss)
Stephen H. Fisher (Agent Quarry)
Garth Cooper (Agent Stone)
Angus MacInnes (Sgt. Whitman)
Jim Howick (Cpl. Matlin)
Brian Steele (Sammael)
Ladislav Beran (Kroenen)