Al Pacino (Lowell Bergman)
Russell Crowe (Jeffrey Wigand)
Christopher Plummer (Mike Wallace)
Diane Venora (Liane Wigand)
Philip Baker Hall (Don Hewitt)
Bruce McGill (Ron Motley)
Gina Gershon (Helen Caperelli)
Michael Gambon (Thomas Sandefur)
Rip Torn (John Scanlon)
Lynne Thigpen (Mrs. Williams)
Hallie Kate Eisenberg (Barbara Wigand)
Michael Paul Chan (Norman the Cameraman)
Linda Hart (Mrs. Wigand)
Robert Harper (Mark Stern)
Nestor Serrano (FBI Agent Robertson)
Pete Hamill (N.Y. Times Reporter)
Wings Hauser (Tobacco Lawyer)
Cliff Curtis (Sheikh Fadlallah)
Renee Olstead (Deborah Wigand)
Michael Moore (Michael Moore)
Lindsay Crouse (Sharon Tiller)
Debi Mazar (Debbie De Luca)
Stephen Tobolowsky (Eric Kluster)
Colm Feore (Richard Scruggs)