Xandra is a given name or a nickname for Alexandra (alternate spelling Zandra). Xandra (Zandra) is the feminine equivalent of Xander (Zander).
Xandra, a Dutch musical group fronted by Dutch singer Sandra Reemer representing Netherlands in the Eurovision Song Contest in 1979,
Xandra no Daibōken: Valkyrie to no Deai, (literally Xandra's Great Adventure: Encounter with the Valkyrie), an action-adventure platform game featuring character Krino Sandra (romanized as Xandra),
Xandra, a character played by Sheryl Cruz in Komiks Presents: Varga,
Xandra, a fictional character in Doom 2099