Number Six may refer to:
Number Six (The Prisoner),
Number Six (Battlestar Galactica),
"Number Six" (song), a song and mini movie by Alice Nine,
"Number Six", a song by Karate from the album Unsolved,
#6 or Shawn Crahan, American musician,
Number Six or Sayaka Suzuki, a character from Pani Poni Dash!,
No. 6, a series of novels by Atsuko Asano.