Or see End-to-end distance.
Embryonic ectoderm development
, Rendering based on PDB 3IIW.
Ortholog search: PDBe, RCSB
List of PDB id codes
3IIW, 3IIY, 3IJ0, 3IJ1, 3IJC, 3JPX, 3JZG, 3JZH, 3JZN, 3K26, 3K27
EED; HEED; WAIT1
OMIM: 605984 MGI: 95286 HomoloGene: 2814 GeneCards: EED Gene
• chromatin binding, • protein binding, • histone methyltransferase activity, • identical protein binding,
• sex chromatin, • nucleus, • ESC/E(Z) complex, • pronucleus,
• regulation of gene expression by genetic imprinting, • transcription, DNA-dependent, • negative regulation of transcription, DNA-dependent,
Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
85.96 - 85.99 Mb
89.95 - 89.98 Mb
Polycomb protein EED is a protein that in humans is encoded by the EED gene.
4 Further reading,
Polycomb protein EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin β7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.
EED has been shown to interact with HDAC1,Histone deacetylase 2,PPP1R8,TGS1,EZH2 and ITGB7.