- Southwind -- SP Bala
- S.P. Balasubrahmaniyam -- Space Morisson
- Space Mtn -- SpaceStorm
- Spacesurfer -- Spank-Loc
- Spank & Major -- Sparky Rucker
- Sparky Rucker -- Speaker/Cranker
- Speaker for the Dead -- Spectac
- Spectacle -- Speedball Baby
- Speedball Jr. -- Spelunkers
- Spen -- Spesimen
- Spesk K -- Spider Monkey
- Spider Nick & The Maddogs -- SPiN
- Spin Aqua -- Spirea X
- Spirea X -- Spiritual Child Meets Devious Minds
- Spiritual Delivers -- Spizzenergi
- Spizzenergi -- Splitter
- Splitter -- Spooky Pie
- Spooky Tooth -- Spraggie
- Sprains -- Spud Mack
- Spud Murphy -- S.Q.