- Otis Gayle
- Otis Gibbs
- Otis Goodnight
- Otis Grand
- Otis Grove
- Otis Harlan
- Otis Hayes
- Otis Hayes III
- Otis Haynes
- Otis Heat
- Otis Horton, Jr.
- Otis Houston Jr.
- Otis Igleman
- Otis Isaacs
- Otis Jackson
- Otis Jackson, Jr.
- Otis Jackson, Sr.
- Otis Johnson
- Otis Jones
- Otis Joseph
- Otis Leavill
- Otis Leaville
- Otis Liggett
- Otis Lisby
- Otis Mannick
- Otis M'Buta
- Otis Monroe
- Otis Mote
- Otis My Man
- Otis Read
- Otis Redding
- Otis Redding & Carla Thomas
- Otis Redding & The Pinetoppers
- Otis Rush
- Otis Rush & Willie Dixon Band
- Otis & Shug
- Otis & Shug
- Otis Smith
- Otis "Smokey" Smothers
- Otis Spann
- Otis Stokes
- Otis & Suge
- Otis T. Rene Jr.
- Otis Taylor
- Otis Thames
- Otis Thompson