Ralph attended school in Angola, then emigrated to New York to finish school where he majored in accounting in college. A former member of an alternative rock band from New York, Anselmo began making projects as a solo artist.
In 1991 and 1992, he resided in Madrid and was greatly influenced by Dominican singer Juan Luis Guerra. In 1995, he returned to Angola forming the hip hop group NGB (standing for Nova Geração Bantu). The group released the album Tá-se Bem the following year on EP Studios (EP standing for Eduardo Paím), although various financial difficulties hampered distribution which lagged until 1999.
In 2000, he returned to New York to try to make it in the States. He was part of a Latin rock band singing in Spanish for the American Latin market, but with limited success again because of disputes with record labels and promoters. In 2001, he also tried promoting songs in English, finding some appeal with universities and religious associations, but no commercial success.
Disappointed he returned to Angola in 2003, working on his Portuguese language album Histórias de Amor, destined for local Angolan and Portuguese markets. The album produced by Aires (Aires no Beat) on the label Bon Som was an immediate success in 2006 in both markets. His concert tour attracted record numbers approaching 6-7 thousand. He was nominated by the Channel O Music Video Awards in the "Best R & B" and "Best Director" categories, and he won the MTV Europe Music Awards 2006 in the "Best African Artist" category. He received the award during a gala in Copenhagen.